Effects of neutral selection on the evolution of molecular species
| dc.creator | Newman, M. E. J. | |
| dc.creator | Engelhardt, Robin | |
| dc.date | 1997-12-15 | |
| dc.date.accessioned | 2026-07-25T10:52:46Z | |
| dc.description | We introduce a new model of evolution on a fitness landscape possessing a tunable degree of neutrality. The model allows us to study the general properties of molecular species undergoing neutral evolution. We find that a number of phenomena seen in RNA sequence-structure maps are present also in our general model. Examples are the occurrence of "common" structures which occupy a fraction of the genotype space which tends to unity as the length of the genotype increases, and the formation of percolating neutral networks which cover the genotype space in such a way that a member of such a network can be found within a small radius of any point in the space. We also describe a number of new phenomena which appear to be general properties of neutrally evolving systems. In particular, we show that the maximum fitness attained during the adaptive walk of a population evolving on such a fitness landscape increases with increasing degree of neutrality, and is directly related to the fitness of the most fit percolating network. | |
| dc.description | 16 pages including 4 postscript figures, typeset in LaTeX2e using the Elsevier macro package elsart.cls | |
| dc.identifier | https://arxiv.org/abs/adap-org/9712005 | |
| dc.identifier | http://arxiv.org/abs/adap-org/9712005 | |
| dc.identifier | Proc. R. Soc. London B 265, 1333-1338 (1998) | |
| dc.identifier.uri | https://dspace.dare.co.zw/handle/123456789/115 | |
| dc.subject | Adaptation and Self-Organizing Systems | |
| dc.subject | Quantitative Biology | |
| dc.title | Effects of neutral selection on the evolution of molecular species | |
| dc.type | text |