IMMUNO-model in Cancer
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Date
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Springer Nature
Humana
Humana
Abstract
Description
This open access volume describes the computational and experimental models that help researchers understand the responses of the immune system in cancer and test experimental immune-oncology approaches. The chapters in this book cover methods such as profile polarization in macrophages using ELISA; immune checkpoint inhibitors; interactions of PD-1/PD-L1 and T cells; immunocompetent preclinical mouse models to study primary and metastatic brain cancer; and methods to generate CAR T-cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Immuno-Model in Cancer: Methods and Protocols is a valuable resource for both new and experienced researchers who want to learn more about this important and developing field.
Keywords
Open Access, Dendritic Cell Activation, breast cancer cell lines, Immunohistochemistry, macrophage polarization, myeloid-derived suppressor cells, MDSC, T-cell killing assay, thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCL Oncology, thema EDItEUR::M Medicine and Nursing::MJ Clinical and internal medicine::MJC Diseases and disorders::MJCM Immunology